Kristiina Ausmees
Division of Scientific Computing
Department of Information Technology
Uppsala University
Uppsala
The analysis of ancient DNA from human remains at archaeological sites is an important tool in inferring human demographic and evolutionary history. Due to the poor quality of such data, modern genomic analysis tools are often not suitable. The goal of my project is to develop new computational methods for analysis of ancient human DNA, with focus on statistical methods for haplotype inference and imputation. In this talk I will outline existing methods, explain the issues in applying these to ancient samples, and discuss methods that are better tailored for the challenges provided in analysis of ancient DNA.